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Anti-ZNHIT2 Polyclonal Antibody

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Catalog No. TMAB-14448

Anti-ZNHIT2 Polyclonal Antibody is a Rabbit antibody targeting ZNHIT2. Anti-ZNHIT2 Polyclonal Antibody can be used in WB.

Anti-ZNHIT2 Polyclonal Antibody

Anti-ZNHIT2 Polyclonal Antibody

😃Good
Catalog No. TMAB-14448
Anti-ZNHIT2 Polyclonal Antibody is a Rabbit antibody targeting ZNHIT2. Anti-ZNHIT2 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-ZNHIT2 Polyclonal Antibody is a Rabbit antibody targeting ZNHIT2. Anti-ZNHIT2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Pig)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityLow expression in most tissues; highly expressed in testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundZNHIT2 (zinc finger, HIT-type containing 2), also known as FON, is a 403 amino acid protein that is highly expressed in the seminiferous tubules of testis, with low expression in other tissues. Containing one HIT-type zinc finger, ZNHIT2 is encoded by a gene that maps to human chromosome 11, which comprises approximately 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and thalassemia are caused by HBB gene mutations, while Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11-encoded genes.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human ZNHIT2
Antigen Species
Human
Gene Name
ZNHIT2
Gene ID
Protein Name
Zinc finger HIT domain-containing protein 2
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 45 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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