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Anti-Estrogen Related Receptor beta Polyclonal Antibody

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Catalog No. TMAB-05708

Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB.

Anti-Estrogen Related Receptor beta Polyclonal Antibody

Anti-Estrogen Related Receptor beta Polyclonal Antibody

😃Good
Catalog No. TMAB-05708
Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNuclear
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
FormulationPreservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4.
Concentration1mg/ml
Research BackgroundEstrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Estrogen Related Receptor beta
Antigen Species
Human
Gene Name
ESRRB
Gene ID
2103
Protein Name
Steroid hormone receptor ERR2
Uniprot ID
O95718
Function
Nuclear receptor that binds DNA as monomer.
Chemical Properties
Molecular WeightTheoretical: 56 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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