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Anti-Estrogen Related Receptor beta Polyclonal Antibody
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Catalog No. TMAB-05708 Copy Product Info
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Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB.
Anti-Estrogen Related Receptor beta Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $220 | 7-10 days | 7-10 days | |
| 100 µL | $374 | 7-10 days | 7-10 days | |
| 200 µL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Antigen Details
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| Description | Anti-Estrogen Related Receptor beta Polyclonal Antibody is a Rabbit antibody targeting Estrogen Related Receptor beta. Anti-Estrogen Related Receptor beta Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Rabbit) |
| Verified Activity | 1. Sample: Cerebrum (Mouse) Lysate at 40 μg Primary: Anti-Estrogen Related Receptor betA (TMAB-05708) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD 2. Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-Estrogen Related Receptor betA (TMAB-05708) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kD Observed band size: 56 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nuclear |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | Estrogen related receptor beta, a NR3 Steroid Receptor, has been shown to affect early placental development. Also it can act as a repressor of transcriptional activity mediated by the glucocorticoid receptor (GR). It binds as a monomer to the extended half-site TNAAGTGCA and as a homodimer to the estrogen response element (ERE), palindromic thyroid hormone response element (TRE(pal)), and SF-1 response element, but not to the glucocorticoid response element (GRE). Estrogen related receptor beta mutations lead to abnormal development of the chorion and defective diploid trophoblast proliferation, and are lethal during midgestation. Expression has been documented in mice in the extraembryonic ectoderm that gives rise to the chorion. ESTs have been isolated from normal human eye, lung, and testis libraries. The ligand for the receptor is PPARgamma coactivator 1 (PGC-1) beta. |
| Immunogen | KLH conjugated synthetic peptide: human Estrogen Related Receptor beta |
| Antigen Species | Human |
| Gene Name | ESRRB |
| Gene ID | |
| Protein Name | Steroid hormone receptor ERR2 |
| Uniprot ID | |
| Function | Nuclear receptor that binds DNA as monomer. |
| Molecular Weight | Theoretical: 56 kDa. Actual: 56 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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