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Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody

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Catalog No. TMAB-10938

Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP4K4 (Ser801). Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody

Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody

😃Good
Catalog No. TMAB-10938
Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP4K4 (Ser801). Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MAP4K4 (Ser801). Anti-Phospho-MAP4K4 (Ser801) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Chicken,Dog,Horse,Rabbit)
Application
WB
IHC-P
IHC-Fr
IF
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
Tissue SpecificityAppears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human MAP4K4 around the phosphorylation site of Ser801
Antigen Species
Human
Gene Name
MAP4K4
Gene ID
9448
Protein Name
Mitogen-activated protein kinase kinase kinase kinase 4
Uniprot ID
O95819
Function
Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.
Chemical Properties
Molecular WeightTheoretical: 142 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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