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Anti-DOPEY2 Polyclonal Antibody

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Catalog No. TMAB-05291

Anti-DOPEY2 Polyclonal Antibody is a Rabbit antibody targeting DOPEY2. Anti-DOPEY2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-DOPEY2 Polyclonal Antibody

Anti-DOPEY2 Polyclonal Antibody

😃Good
Catalog No. TMAB-05291
Anti-DOPEY2 Polyclonal Antibody is a Rabbit antibody targeting DOPEY2. Anti-DOPEY2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-DOPEY2 Polyclonal Antibody is a Rabbit antibody targeting DOPEY2. Anti-DOPEY2 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Cow,Horse,Sheep)
Application
IHC-P
IHC-Fr
IF
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityUbiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundDopey-2 is a 2,298 amino acid protein that is ubiquitously expressed with high levels found in the developing central nervous system where it is thought to play a role in protein trafficking between early endosomes and the late Golgi. Multiple isoforms of Dopey-2 exist due to alternative splicing events. The gene encoding Dopey-2 maps to human chromosome 21 and may be involved in the pathogenesis of Down syndrome. The smallest of the human chromosomes, chromosome 21 comprises about 1.5% of the human genome and contains nearly 300 genes and 47 million base pairs. Down syndrome, also known as trisomy 21, is the disease most commonly associated with chromosome 21. Alzheimer's disease, Jervell and Lange-Nielsen syndrome and amyotrophic lateral sclerosis are also associated with chromosome 21. Translocations are found to occur between chromosome 21 and 8, and chromosome 21 and 12, in certain leukemias.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DOPEY2
Antigen Species
Human
Gene Name
DOP1B
Gene ID
9980
Protein Name
Protein dopey-2
Uniprot ID
Q9Y3R5
Function
May be involved in protein traffic between late Golgi and early endosomes.
Chemical Properties
Molecular WeightTheoretical: 258 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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