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Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody

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Catalog No. TMAB-10459

Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody is a Rabbit antibody targeting Phospho-cdc25C (Thr48). Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.

Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody

Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody

😃Good
Catalog No. TMAB-10459
Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody is a Rabbit antibody targeting Phospho-cdc25C (Thr48). Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody is a Rabbit antibody targeting Phospho-cdc25C (Thr48). Anti-Phospho-cdc25C (Thr48) Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human cdc25C around the phosphorylation site of Thr48
Antigen Species
Human
Gene Name
CDC25C
Gene ID
Protein Name
M-phase inducer phosphatase 3
Uniprot ID
Function
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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