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Anti-RASGRP3 Polyclonal Antibody

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Catalog No. TMAB-12110

Anti-RASGRP3 Polyclonal Antibody is a Rabbit antibody targeting RASGRP3. Anti-RASGRP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-RASGRP3 Polyclonal Antibody

Anti-RASGRP3 Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-12110
Anti-RASGRP3 Polyclonal Antibody is a Rabbit antibody targeting RASGRP3. Anti-RASGRP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5287-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-RASGRP3 Polyclonal Antibody is a Rabbit antibody targeting RASGRP3. Anti-RASGRP3 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (RASGRP3) Polyclonal Antibody, Unconjugated (TMAB-12110) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundMembers of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]).[supplied by OMIM, Mar 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human RASGRP3
Antigen Species
Human
Gene Name
RASGRP3
Gene ID
Protein Name
Ras guanyl-releasing protein 3
Uniprot ID
Function
Guanine nucleotide exchange factor (GEF) for Ras and Rap1.
Chemical Properties
Molecular WeightTheoretical: 78 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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