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Anti-SAPS1 Polyclonal Antibody is a Rabbit antibody targeting SAPS1. Anti-SAPS1 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-SAPS1 Polyclonal Antibody is a Rabbit antibody targeting SAPS1. Anti-SAPS1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat (predicted:Dog,Pig,Cow,Horse,Rabbit,Rhesus monkey,Gorilla, Orangutan) |
| Verified Activity | Sample: Lane 1: Stomach (Mouse) Lysate at 40 μg Lane 2: Testis (Mouse) Lysate at 40 μg Lane 3: Lymph node (Mouse) Lysate at 40 μg Lane 4: Testis (Rat) Lysate at 40 μg Lane 5: HL60 (Human) Cell Lysate at 30 μg Lane 6: 293T (Human) Cell Lysate at 30 μg Lane 7: Molt-4 (Human) Cell Lysate at 30 μg Primary: Anti-SAPS1 (TMAB-12501) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 120 kD Observed band size: 120 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm |
| Tissue Specificity | Ubiquitous with higher expression in testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Protein phosphatase regulatory subunits, such as SAPS1, modulate the activity of protein phosphatase catalytic subunits by restricting substrate specificity, recruiting substrates, and determining the intracellular localization of the holoenzyme. SAPS1 is a regulatory subunit for the protein phosphatase-6 catalytic subunit (PPP6C; MIM 612725) (Stefansson and Brautigan, 2006 [PubMed 16769727]).[supplied by OMIM, Nov 2010] |
| Immunogen | KLH conjugated synthetic peptide: human SAPS1 |
| Antigen Species | Human |
| Gene Name | PPP6R1 |
| Gene ID | |
| Protein Name | Serine/threonine-protein phosphatase 6 regulatory subunit 1 |
| Uniprot ID | |
| Function | Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha. |
| Molecular Weight | Theoretical: 97 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
| Size | Quantity | Unit Price | Amount | Operation |
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