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Anti-C9orf3 Polyclonal Antibody is a Rabbit antibody targeting C9orf3. Anti-C9orf3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-C9orf3 Polyclonal Antibody is a Rabbit antibody targeting C9orf3. Anti-C9orf3 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Chicken) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm (Potential). |
| Tissue Specificity | Predominantly expressed in pancreas, placenta, liver, testis and heart. Expressed at lower level in brain, lung and kidney. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | C9orf3 is an aminopeptidase and belongs to the M1 family of metallopeptidases or gluzincins. Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. C9orf3 is able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway but not able to cleave angiotensin I and angiotensin II. It may play a role in the proteolytic processing of bioactive peptides in tissues where it is expressed. C9orf3 is predominantly expressed in pancreas, placenta, liver, testis and heart and at lower level in brain, lung and kidney. There are four named isoforms. |
| Immunogen | KLH conjugated synthetic peptide: human C9orf3 |
| Antigen Species | Human |
| Gene Name | AOPEP |
| Gene ID | |
| Protein Name | Aminopeptidase O |
| Uniprot ID | |
| Function | Aminopeptidases catalyze the hydrolysis of amino acid residues from the N-terminus of peptide or protein substrates. Able to cleave angiotensin III to generate angiotensin IV, a bioactive peptide of the renin-angiotensin pathway. Not able to cleave angiotensin I and angiotensin II. May play a role in the proteolytic processing of bioactive peptides in tissues such as testis and heart. |
| Molecular Weight | Theoretical: 94 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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