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Anti-SEMA4D Monoclonal Antibody-Biotin
(Synonyms: Semaphorin-4D, GR3, BB18, A8) Copy Product Info
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Synonyms: Semaphorin-4D, GR3, BB18, A8
Catalog No. TMAZ-0130B Copy Product Info
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Anti-SEMA4D Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody-Biotin can be used in FCM.
Anti-SEMA4D Monoclonal Antibody-Biotin
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 μg | $195 | 12 days | 12 days | |
| 50 μg | $234 | 12 days | 12 days | |
| 100 μg | $327 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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| Description | Anti-SEMA4D Monoclonal Antibody-Biotin is a biotin-conjugated humanized rabbit antibody targeting SEMA4D. Anti-SEMA4D Monoclonal Antibody-Biotin can be used in FCM. |
| Synonyms | Semaphorin-4D, GR3, BB18, A8 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10^6 cells for FCM |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of SEMA4D protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cell surface receptor for PLXNB1 and PLXNB2 that plays an important role in cell-cell signaling (PubMed: 20877282). Regulates GABAergic synapse development (By similarity). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner (By similarity). Modulates the complexity and arborization of developing neurites in hippocampal neurons by activating PLXNB1 and interaction with PLXNB1 mediates activation of RHOA (PubMed: 19788569). Promotes the migration of cerebellar granule cells (PubMed: 16055703). Plays a role in the immune system; induces B-cells to aggregate and improves their viability (in vitro) (PubMed: 8876214). Induces endothelial cell migration through the activation of PTK2B/PYK2, SRC, and the phosphatidylinositol 3-kinase-AKT pathway (PubMed: 16055703) |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | SEMA4D |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer Research |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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