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Anti-GCLM Polyclonal Antibody 2
Catalog No. TMAB-06386 Copy Product Info
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Anti-GCLM Polyclonal Antibody 2 is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-GCLM Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-06386
Anti-GCLM Polyclonal Antibody 2 is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-GCLM Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GCLM Polyclonal Antibody 2 is a Rabbit antibody targeting GCLM. Anti-GCLM Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (rat liver tissue); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (GCLM) Polyclonal Antibody, Unconjugated (TMAB-06386) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytosol |
| Tissue Specificity | In all tissues examined. Highest levels in skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015] |
| Immunogen | KLH conjugated synthetic peptide: human GCLM |
| Antigen Species | Human |
| Gene Name | GCLM |
| Gene ID | |
| Protein Name | Glutamate--cysteine ligase regulatory subunit |
| Uniprot ID | |
| Function | This protein is involved in step 1 of the subpathway that synthesizes glutathione from L-cysteine and L-glutamate. |
| Molecular Weight | Theoretical: 31 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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