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Anti-NKRF Polyclonal Antibody

Catalog No. TMAB-09501 Copy Product Info
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Anti-NKRF Polyclonal Antibody is a Rabbit antibody targeting NKRF. Anti-NKRF Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NKRF Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-09501

Anti-NKRF Polyclonal Antibody is a Rabbit antibody targeting NKRF. Anti-NKRF Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-NKRF Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NKRF Polyclonal Antibody is a Rabbit antibody targeting NKRF. Anti-NKRF Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Horse,Rabbit,Sheep)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (NKRF) Polyclonal Antibody, Unconjugated (TMAB-09501) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNuclear
Tissue SpecificityWidely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a transcriptional repressor that interacts with specific negative regulatory elements to mediate transcriptional repression of certain nuclear factor kappa B responsive genes. The protein localizes predominantly to the nucleolus with a small fraction found in the nucleoplasm and cytoplasm. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human NKRF
Antigen Species
Human
Gene Name
NKRF
Gene ID
Protein Name
NF-kappa-B-repressing factor
Uniprot ID
Function
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK-kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Chemical Properties
Molecular WeightTheoretical: 78 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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