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Anti-MEPE Polyclonal Antibody
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Catalog No. TMAB-08752 Copy Product Info
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Anti-MEPE Polyclonal Antibody is a Rabbit antibody targeting MEPE. Anti-MEPE Polyclonal Antibody can be used in WB.
Anti-MEPE Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 µL | $220 | 7-10 days | 7-10 days | |
| 100 µL | $371 | 7-10 days | 7-10 days | |
| 200 µL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MEPE Polyclonal Antibody is a Rabbit antibody targeting MEPE. Anti-MEPE Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Mouse Spleen tissue lysates Lane 4: Mouse Cerebellum tissue lysates Lane 5: Human HepG2 cell lysates Lane 6: Human MCF-7 cell lysates Primary: Anti-MEPE (TMAB-08752) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 47, 62 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted |
| Tissue Specificity | Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers. |
| Immunogen | KLH conjugated synthetic peptide: human MEPE |
| Antigen Species | Human |
| Gene Name | MEPE |
| Gene ID | |
| Protein Name | Matrix extracellular phosphoglycoprotein |
| Uniprot ID | |
| Function | Seems to play a role in mineralization. |
| Molecular Weight | Theoretical: 56 kDa. Actual: 47,62 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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