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Anti-IL2RA/CD25 Polyclonal Antibody

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Catalog No. TMAB-07653

Anti-IL2RA/CD25 Polyclonal Antibody is a Rabbit antibody targeting IL2RA/CD25. Anti-IL2RA/CD25 Polyclonal Antibody can be used in WB,FCM.

Anti-IL2RA/CD25 Polyclonal Antibody

Anti-IL2RA/CD25 Polyclonal Antibody

😃Good
Catalog No. TMAB-07653
Anti-IL2RA/CD25 Polyclonal Antibody is a Rabbit antibody targeting IL2RA/CD25. Anti-IL2RA/CD25 Polyclonal Antibody can be used in WB,FCM.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IL2RA/CD25 Polyclonal Antibody is a Rabbit antibody targeting IL2RA/CD25. Anti-IL2RA/CD25 Polyclonal Antibody can be used in WB,FCM.
Ig Type
IgG
Reactivity
Human,Mouse (predicted:Rat)
Application
WB
FCM
Recommended Dose
WB: 1:500-2000; FCM: 0.2ug /test
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse CD25
Antigen Species
Mouse
Gene Name
IL2RA
Gene ID
16184
Protein Name
Interleukin-2 receptor subunit alpha
Uniprot ID
P01590
Function
Receptor for interleukin-2.
Chemical Properties
Molecular WeightTheoretical: 28 kDa. Actual: 55 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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