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Anti-VLDL Receptor Polyclonal Antibody 2

Catalog No. TMAB-14118 Copy Product Info
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Anti-VLDL Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting VLDL Receptor. Anti-VLDL Receptor Polyclonal Antibody 2 can be used in ICC/IF.

Anti-VLDL Receptor Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-14118

Anti-VLDL Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting VLDL Receptor. Anti-VLDL Receptor Polyclonal Antibody 2 can be used in ICC/IF.

Anti-VLDL Receptor Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2237-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VLDL Receptor Polyclonal Antibody 2 is a Rabbit antibody targeting VLDL Receptor. Anti-VLDL Receptor Polyclonal Antibody 2 can be used in ICC/IF.
Ig Type
IgG
Reactivity
Human
Verified Activity
Hela cell; 4% Paraformaldehyde-fixed; Triton X-100 at room temperature for 20 min; Blocking buffer (normal goat serum) at 37°C for 20 min; Antibody incubation with (VLDL Receptor) polyclonal Antibody, Unconjugated (TMAB-14118) 1:100, 90 minutes at 37°C; followed by a conjugated Goat Anti-Rabbit IgG antibody at 37°C for 90 minutes, DAPI (blue) was used to stain the cell nuclei.
Application
Recommended Dose
ICC/IF: 1:50-200
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein.
Tissue SpecificityAbundant in heart and skeletal muscle; also ovary and kidney; not in liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundVLDL (very low density lipoprotein) cholesterol is one of the three major types of cholesterol found in blood. VLDL receptor plays an essential role in triglyceride metabolism. It binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human VLDL Receptor
Antigen Species
Human
Gene Name
VLDLR
Gene ID
Protein Name
Very low-density lipoprotein receptor
Uniprot ID
Function
Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).
Chemical Properties
Molecular WeightTheoretical: 93 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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