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Anti-GFRA4 Polyclonal Antibody
😃Good
Catalog No. TMAB-06452
Anti-GFRA4 Polyclonal Antibody is a Rabbit antibody targeting GFRA4. Anti-GFRA4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-GFRA4 Polyclonal Antibody
Anti-GFRA4 Polyclonal Antibody
😃Good
Catalog No. TMAB-06452
Anti-GFRA4 Polyclonal Antibody is a Rabbit antibody targeting GFRA4. Anti-GFRA4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GFRA4 Polyclonal Antibody is a Rabbit antibody targeting GFRA4. Anti-GFRA4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform GFRalpha4a: Cell membrane; Lipid-anchor, GPI-anchor. Isoform GFRalpha4b: Cell membrane; Lipid-anchor, GPI-anchor. Isoform GFRalpha4c: Secreted. |
| Tissue Specificity | Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for persephin, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for RET-associated diseases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq] |
| Immunogen | KLH conjugated synthetic peptide: human GFRA4 |
| Antigen Species | Human |
| Gene Name | GFRA4 |
| Gene ID | |
| Protein Name | GDNF family receptor alpha-4 |
| Uniprot ID | |
| Function | Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla. |
| Molecular Weight | Theoretical: 27 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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