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Anti-DUSP6 Polyclonal Antibody 3

Catalog No. TMAB-05349 Copy Product Info
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Anti-DUSP6 Polyclonal Antibody 3 is a Rabbit antibody targeting DUSP6. Anti-DUSP6 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-DUSP6 Polyclonal Antibody 3

Copy Product Info
🥰Excellent
Catalog No. TMAB-05349

Anti-DUSP6 Polyclonal Antibody 3 is a Rabbit antibody targeting DUSP6. Anti-DUSP6 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.

Anti-DUSP6 Polyclonal Antibody 3
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-DUSP6 Polyclonal Antibody 3 is a Rabbit antibody targeting DUSP6. Anti-DUSP6 Polyclonal Antibody 3 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Cow,Horse,Rabbit)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (human gastric carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (DUSP6) Polyclonal Antibody, Unconjugated (TMAB-05349) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human DUSP6
Antigen Species
Human
Gene Name
DUSP6
Gene ID
Protein Name
Dual specificity protein phosphatase 6
Uniprot ID
Function
Inactivates MAP kinases. Has a specificity for the ERK family.
Chemical Properties
Molecular WeightTheoretical: 42 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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