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Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody
😃Good
Catalog No. TMAB-12979
Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody is a Rabbit antibody targeting smooth muscle Myosin heavy chain 11. Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody
Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody
😃Good
Catalog No. TMAB-12979
Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody is a Rabbit antibody targeting smooth muscle Myosin heavy chain 11. Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody is a Rabbit antibody targeting smooth muscle Myosin heavy chain 11. Anti-smooth muscle Myosin heavy chain 11 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Thick filaments of the myofibrils. |
| Tissue Specificity | Smooth muscle; expressed in the umbilical artery, bladder, esophagus and trachea. |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. The gene encoding a human ortholog of rat NUDE1 is transcribed from the reverse strand of this gene, and its 3' end overlaps with that of the latter. The pericentric inversion of chromosome 16[inv(16)(p13q22)] produces a chimeric transcript that encodes a protein consisting of the first 165 residues from the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Alternative splicing generates isoforms that are differentially expressed, with ratios changing during muscle cell maturation. Alternatively spliced transcript variants encoding different isoforms have been identified. MYH11 is a smooth muscle myosin belonging to the myosin heavy chain family. It is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. |
| Immunogen | KLH conjugated synthetic peptide: human smooth muscle Myosin heavy chain 11 |
| Antigen Species | Human |
| Gene Name | MYH11 |
| Gene ID | |
| Protein Name | Myosin-11 |
| Uniprot ID | |
| Function | Muscle contraction. |
| Molecular Weight | Theoretical: 227 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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