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Anti-Serine racemase Polyclonal Antibody

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Catalog No. TMAB-12676

Anti-Serine racemase Polyclonal Antibody is a Rabbit antibody targeting Serine racemase. Anti-Serine racemase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.

Anti-Serine racemase Polyclonal Antibody

Anti-Serine racemase Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-12676
Anti-Serine racemase Polyclonal Antibody is a Rabbit antibody targeting Serine racemase. Anti-Serine racemase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-Serine racemase Polyclonal Antibody is a Rabbit antibody targeting Serine racemase. Anti-Serine racemase Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human,Mouse,Rat (predicted:Dog,Cow,Rabbit,Sheep)
Verified Activity
1. Tissue/cell: rat kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-Serine racemase Polyclonal Antibody, Unconjugated (TMAB-12676) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
2. Sample: lovo (Human) Cell Lysate at 40 μg
Primary: Anti-Serine racemase (TMAB-12676) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
3. Sample: Liver (Mouse) Lysate at 40 μg
Primary: Anti-Serine racemase (TMAB-12676) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 37 kD
Observed band size: 37 kD
Application
Recommended Dose
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityBrain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundKnown to be prominent in bacteria, D amino acids were generally thought to be absent in mammals. D-serine has since been found in high levels in the mammalian brain and in various mammalian fluids. D-serine activates N-methyl-D-aspartate (NMDA) receptors--molecules with important roles in learning, brain growth and brain cell death. Serine racemase is the enzyme catalyzing the formation of D-serine from L-serine. Serine racemase is a member of the family of pyridoxal-5’ phosphate-dependent enzymes and is localized to glial cells in rat brain.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human Serine racemase
Antigen Species
Human
Gene Name
SRR
Gene ID
Protein Name
Serine racemase
Uniprot ID
Function
Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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