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Anti-AMPK beta 2 Polyclonal Antibody 2
Catalog No. TMAB-02534 Copy Product Info
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Anti-AMPK beta 2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMPK beta 2. Anti-AMPK beta 2 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-AMPK beta 2 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-02534
Anti-AMPK beta 2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMPK beta 2. Anti-AMPK beta 2 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Anti-AMPK beta 2 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-AMPK beta 2 Polyclonal Antibody 2 is a Rabbit antibody targeting AMPK beta 2. Anti-AMPK beta 2 Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human) |
| Verified Activity | Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (AMPK beta 2) Polyclonal Antibody, Unconjugated (TMAB-02534) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Highly expressed in kidney, heart, white adipose tissue, lung and spleen. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status and plays a role in protecting cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase (ACC). It also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase (HMGCR) and hormone-sensitive lipase. PRKAB2 may be a positive regulator of AMPK activity. |
| Immunogen | KLH conjugated synthetic peptide: human AMPK beta 2 |
| Antigen Species | Human |
| Gene Name | PRKAB2 |
| Gene ID | |
| Protein Name | 5'-AMP-activated protein kinase subunit beta-2 |
| Uniprot ID | |
| Function | AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit. |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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