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Anti-IGSF8 Polyclonal Antibody
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Catalog No. TMAB-07568
Anti-IGSF8 Polyclonal Antibody is a Rabbit antibody targeting IGSF8. Anti-IGSF8 Polyclonal Antibody can be used in FCM.
Anti-IGSF8 Polyclonal Antibody
Anti-IGSF8 Polyclonal Antibody
😃Good
Catalog No. TMAB-07568
Anti-IGSF8 Polyclonal Antibody is a Rabbit antibody targeting IGSF8. Anti-IGSF8 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-IGSF8 Polyclonal Antibody is a Rabbit antibody targeting IGSF8. Anti-IGSF8 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Cow,Horse) |
| Application | |
| Recommended Dose | FCM: 1μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane; Single-pass membrane protein. |
| Tissue Specificity | Expressed in lymphocytes as well as in many tissues with higher expression in brain. Detected in all regions of the brain with weak expression in the pituitary. Expressed selectively by neurons but not by glial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | IGSF8 is a 65kDa single-pass membrane protein that may play a key role in many of the functions attributed to CD81 and CD9, like Hepatitis C infection and oocyte fertilization. It is also believed that this protein acts as a negative regulator of cell motility (e.g. T-cell mobility, prostate cancer cell migration) and is involved in the regulation of neurite outgrowth and maintenance of the neural network in the brain. |
| Immunogen | KLH conjugated synthetic peptide: mouse IGSF8 |
| Antigen Species | Mouse |
| Gene Name | IGSF8 |
| Gene ID | |
| Protein Name | Immunoglobulin superfamily member 8 |
| Uniprot ID | |
| Function | May play a key role in diverse functions ascribed to CD81 and CD9 such as oocytes fertilization or hepatitis C virus function. May regulate proliferation and differentiation of keratinocytes. May be a negative regulator of cell motility: suppresses T-cell mobility coordinately with CD81, associates with CD82 to suppress prostate cancer cell migration, regulates epidermoid cell reaggregation and motility on laminin-5 with CD9 and CD81 as key linkers. May also play a role on integrin-dependent morphology and motility functions. May participate in the regulation of neurite outgrowth and maintenance of the neural network in the adult brain. |
| Molecular Weight | Theoretical: 62 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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