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Anti-EFNB2 Monoclonal Antibody
(Synonyms: HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5) Copy Product Info
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Synonyms: HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5
Catalog No. TMAZ-0210 Copy Product Info
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Anti-EFNB2 Monoclonal Antibody is a humanized rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in FCM.
Anti-EFNB2 Monoclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 25 µg | $405 | 12 days | 12 days | |
| 50 µg | $486 | 12 days | 12 days | |
| 100 µg | $680 | 12 days | 12 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Liquid
Color:Transparent
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| Description | Anti-EFNB2 Monoclonal Antibody is a humanized rabbit antibody targeting EFNB2. Anti-EFNB2 Monoclonal Antibody can be used in FCM. |
| Synonyms | HTK ligand, Ephrin-B2, EPH-related receptor tyrosine kinase ligand 5 |
| Ig Type | Rabbit monoclonal IgG |
| Reactivity | Human |
| Verified Activity | Flow cytometry analysis of EFNB2 overexpressed 429F cells with TMAZ-0210, followed by goat anti-rabbit IgG-ABflo 647 (red line). The isotype control is rabbit IgG (black line). |
| Application | |
| Recommended Dose | 0.1-0.2 μg/10^6 cells for FCM |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Subcellular Localization | Single-pass type I membrane |
| Construction | This antibody was produced from a rabbit immunized with purified, recombinant human extracellular domain of EFNB2 protein. |
| Purification | Protein A Affinity Purified |
| Appearance | Liquid |
| Formulation | 0.22 μm filtered solution in PBS. |
| Purity | > 95% as determined by SDS-PAGE. |
| Research Background | Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons|(Microbial infection) Acts as a receptor for Hendra virus and Nipah virus |
| Conjucates | Unconjugated |
| Others Formats | Biotin |
| Antibody Types Available | 2 |
| Immunogen | EFNB2 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cytokines |
| Molecular Weight | 150 kDa |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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