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Anti-eIF3F Polyclonal Antibody

Catalog No. TMAB-05504 Copy Product Info
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Anti-eIF3F Polyclonal Antibody is a Rabbit antibody targeting eIF3F. Anti-eIF3F Polyclonal Antibody can be used in WB.

Anti-eIF3F Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05504

Anti-eIF3F Polyclonal Antibody is a Rabbit antibody targeting eIF3F. Anti-eIF3F Polyclonal Antibody can be used in WB.

Anti-eIF3F Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-eIF3F Polyclonal Antibody is a Rabbit antibody targeting eIF3F. Anti-eIF3F Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Chicken,Dog,Cow,Horse)
Verified Activity
Sample: Small intestine (Mouse) Lysate at 40 μg
Primary: Anti-eIF3F (TMAB-05504) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 38 kD
Observed band size: 38 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundEIF3F, (also known as eukaryotic translation initiation factor 3 subunit 5, EIF-3 epsilon, and EIF3 p47 subunit), is part of the EIF3 complex, which is composed of at least 12 subunits. It binds the 40S ribosome and promotes the binding of methionyl-tRNAi and mRNA. It can bind the COP9 signalosome and the 26S proteasome, possibly having regulatory functions in both protein translation and degradation. EIF3F also associates with the complex p170-EIF3.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human eIF3F
Antigen Species
Human
Gene Name
EIF3F
Gene ID
Protein Name
Eukaryotic translation initiation factor 3 subunit F
Uniprot ID
Function
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling.
Chemical Properties
Molecular WeightTheoretical: 38 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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