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Anti-LRP5L Polyclonal Antibody
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Catalog No. TMAB-08402
Anti-LRP5L Polyclonal Antibody is a Rabbit antibody targeting LRP5L. Anti-LRP5L Polyclonal Antibody can be used in WB.
Anti-LRP5L Polyclonal Antibody
Anti-LRP5L Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-08402
Anti-LRP5L Polyclonal Antibody is a Rabbit antibody targeting LRP5L. Anti-LRP5L Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-LRP5L Polyclonal Antibody is a Rabbit antibody targeting LRP5L. Anti-LRP5L Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Chicken,Sheep) |
| Verified Activity | 1. Sample: U2os (Human) Cell Lysate at 30 μg 293T (Human) Cell Lysate at 30 μg Primary: Anti-LRP5L (TMAB-08402) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD 2. Sample: U2Os (Human) Cell Lysate at 30 μg Primary: Anti-LRP5L (TMAB-08402) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 28 kD Observed band size: 28 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Members of the LDL receptor gene family, including LDLR (low density lipo-protein receptor), LRPs (low density lipoprotein related proteins), Megalin (also designated GP330), VLDLR (very low density lipoprotein receptor) and ApoER2, are characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. Of the known family members, LRP5 is most closely related to LRP1. However, LRP5 has a unique organization of EGF and LDLR repeats compared to other LDLR family members and likely represents a new category in this family. LRP is expressed in rat tibia, specifically in areas of the bone that are involved in remodeling. LRP5 is a Wnt coreceptor that binds to Axin and regulates the canonical Wnt signaling pathway. LRP5 affects bone mass accrual during growth. Mutations in LRP5 cause the autosomal recessive disorder osteoporosis-pseudoglioma syndrome (OPPG). LRP5L is a related protein that exists as two isoforms produced by alternative splicing. |
| Immunogen | KLH conjugated synthetic peptide: human LRP5L |
| Antigen Species | Human |
| Gene Name | LRP5L |
| Gene ID | |
| Protein Name | Low-density lipoprotein receptor-related protein 5-like protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 28 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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