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Anti-BDKRB1 Polyclonal Antibody 3

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Catalog No. TMAB-03078

Anti-BDKRB1 Polyclonal Antibody 3 is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody 3 can be used in WB.

Anti-BDKRB1 Polyclonal Antibody 3

Anti-BDKRB1 Polyclonal Antibody 3

😃Good
Catalog No. TMAB-03078
Anti-BDKRB1 Polyclonal Antibody 3 is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody 3 can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2237-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-BDKRB1 Polyclonal Antibody 3 is a Rabbit antibody targeting BDKRB1. Anti-BDKRB1 Polyclonal Antibody 3 can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundKinins are important biologically active peptides that mediate cardiovascular homeostasis, inflammation and nociception. Bradykinin, the major effector peptide of the kallikrein-kinin system, is regulated by angiotensin-converting enzyme (ACE), which degrades the peptide. Bradykinin normally exerts its effects through the activation of two seven transmembrane G-protein coupled receptors, named B1 and B2. The B2 receptor is constitutively expressed and preferentially binds full length bradykinin. Deletion of the B2 receptor leads to salt-sensitive hypertension and altered nociception in mice. The B1 receptor binds to derivatives of bradykinin and kallidin, which are produced by carboxypeptidase action to generate the products des-Arg9-bradykinin and des-Arg10-kallidin, respectively. The expression of the B1 receptor is inducible by inflammatory mediators, such as bacterial lipopolysaccharide (LPS) and cytokines. The B1 and B2 receptors represent potential therapeutic targets for treatment of inflammatory disorders and cardiovascular diseases.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human BDKRB1
Antigen Species
Human
Gene Name
BDKRB1
Gene ID
623
Protein Name
B1 bradykinin receptor
Uniprot ID
P46663
Function
This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation.
Chemical Properties
Molecular WeightTheoretical: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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