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Anti-GSTA3 Polyclonal Antibody

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Catalog No. TMAB-06824

Anti-GSTA3 Polyclonal Antibody is a Rabbit antibody targeting GSTA3. Anti-GSTA3 Polyclonal Antibody can be used in WB.

Anti-GSTA3 Polyclonal Antibody

Anti-GSTA3 Polyclonal Antibody

😃Good
Catalog No. TMAB-06824
Anti-GSTA3 Polyclonal Antibody is a Rabbit antibody targeting GSTA3. Anti-GSTA3 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-GSTA3 Polyclonal Antibody is a Rabbit antibody targeting GSTA3. Anti-GSTA3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Rat (predicted:Mouse)
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Glutathione S-transferase A3 (GSTA3) belongs to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. GSTA3 catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: mouse GSTA3
Antigen Species
Mouse
Gene Name
GSTA3
Gene ID
Protein Name
Glutathione S-transferase A3
Uniprot ID
Function
Conjugation of reduced glutathione to a wide number ofexogenous and endogenous hydrophobic electrophiles. Catalyzesisomerization reactions that contribute to the biosynthesis ofsteroid hormones. Efficiently catalyze obligatory double-bondisomerizations of delta(5)-androstene-3,17-dione anddelta(5)-pregnene-3,20-dione, precursors to testosterone andprogesterone, respectively.
Chemical Properties
Molecular WeightTheoretical: 25 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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