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Anti-IKBKE/IKKi/IKKe Polyclonal Antibody

Catalog No. TMAB-07575 Copy Product Info
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Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-07575

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Cow)
Verified Activity
Tissue/cell: human cervical carcinoma; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-IKBKE/IKKi Polyclonal Antibody, Unconjugated (TMAB-07575) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Nucleus, PML body.
Tissue SpecificityHighly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis member of the Ser/Thr protein kinase family (IkappaB kinase subfamily) phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It is highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta, and may play a special role in the immune response; it is weakly expressed in lung, kidney, prostate, ovary and colon. IKKi/IKKe is also overexpressed in breast cancers.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IKBKE
Antigen Species
Human
Gene Name
IKBKE
Gene ID
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Uniprot ID
Function
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.
Chemical Properties
Molecular WeightTheoretical: 79 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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