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Anti-IKBKE/IKKi/IKKe Polyclonal Antibody

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Catalog No. TMAB-07575

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody

Anti-IKBKE/IKKi/IKKe Polyclonal Antibody

😃Good
Catalog No. TMAB-07575
Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-IKBKE/IKKi/IKKe Polyclonal Antibody is a Rabbit antibody targeting IKBKE/IKKi/IKKe. Anti-IKBKE/IKKi/IKKe Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Cow)
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCytoplasm. Nucleus. Nucleus, PML body.
Tissue SpecificityHighly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis member of the Ser/Thr protein kinase family (IkappaB kinase subfamily) phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. It is highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta, and may play a special role in the immune response; it is weakly expressed in lung, kidney, prostate, ovary and colon. IKKi/IKKe is also overexpressed in breast cancers.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human IKBKE
Antigen Species
Human
Gene Name
IKBKE
Gene ID
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit epsilon
Uniprot ID
Function
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage-induced cell death.
Chemical Properties
Molecular WeightTheoretical: 79 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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