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Anti-P2RX5 Polyclonal Antibody
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Catalog No. TMAB-09853
Anti-P2RX5 Polyclonal Antibody is a Rabbit antibody targeting P2RX5. Anti-P2RX5 Polyclonal Antibody can be used in WB.
Anti-P2RX5 Polyclonal Antibody
Anti-P2RX5 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-09853
Anti-P2RX5 Polyclonal Antibody is a Rabbit antibody targeting P2RX5. Anti-P2RX5 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
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| Description | Anti-P2RX5 Polyclonal Antibody is a Rabbit antibody targeting P2RX5. Anti-P2RX5 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep) |
| Verified Activity | Sample: Heart (Mouse) Lysate at 40 μg Primary: Anti-P2RX5 (TMAB-09853) at 1/300 dilution Secondary: HRP conjugated Goat-Anti-rabbit IgG at 1/5000 dilution Predicted band size: 47 kD Observed band size: 47 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed at high levels in brain and immune system. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP. |
| Immunogen | KLH conjugated synthetic peptide: human P2RX5 |
| Antigen Species | Human |
| Gene Name | P2RX5 |
| Gene ID | |
| Protein Name | P2X purinoceptor 5 |
| Uniprot ID | |
| Function | P2X5b belongs to the family of purinoceptors for ATP. This receptor functions as a ligand gated ion channel. Several characteristic motifs of ATP gated channels are present in its primary structure, but, unlike other members of the purinoceptors family, this receptor has only a single transmembrane domain. Three transcript variants encoding distinct isoforms have been identified for this gene. |
| Molecular Weight | Theoretical: 47 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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