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Anti-Myozenin 2 Polyclonal Antibody
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Catalog No. TMAB-09190
Anti-Myozenin 2 Polyclonal Antibody is a Rabbit antibody targeting Myozenin 2. Anti-Myozenin 2 Polyclonal Antibody can be used in WB.
Anti-Myozenin 2 Polyclonal Antibody
Anti-Myozenin 2 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-09190
Anti-Myozenin 2 Polyclonal Antibody is a Rabbit antibody targeting Myozenin 2. Anti-Myozenin 2 Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Bioactivity
Antigen Details
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| Description | Anti-Myozenin 2 Polyclonal Antibody is a Rabbit antibody targeting Myozenin 2. Anti-Myozenin 2 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Lane 1: Mouse Heart tissue lysates Lane 2: Mouse Cerebrum tissue lysates Lane 3: Rat Cerebrum tissue lysates Primary: Anti-Myozenin 2 (TMAB-09190) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kDa Observed band size: 32 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > myofibril > sarcomere > Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. |
| Tissue Specificity | Expressed specifically in heart and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder. [provided by RefSeq, Aug 2011] |
| Immunogen | KLH conjugated synthetic peptide: human Myozenin 2 |
| Antigen Species | Human |
| Gene Name | MYOZ2 |
| Gene ID | |
| Protein Name | Myozenin-2 |
| Uniprot ID | |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis. |
| Molecular Weight | Theoretical: 30 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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