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Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody
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Catalog No. TMAB-10886
Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITGB2 (Ser756). Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody can be used in IHC-P,IF.
Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody
Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody
😃Good
Catalog No. TMAB-10886
Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITGB2 (Ser756). Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody can be used in IHC-P,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITGB2 (Ser756). Anti-Phospho-ITGB2 (Ser756) Polyclonal Antibody can be used in IHC-P,IF. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The product of this gene belongs to the integrin beta chain family of proteins. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. This gene encodes the integrin beta chain beta 2. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Defects in this gene are the cause of leukocyte adhesion deficiency type I (LAD1). Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human CD18 around the phosphorylation site of Ser756 |
| Antigen Species | Human |
| Gene Name | ITGB2 |
| Gene ID | |
| Protein Name | Integrin beta-2 |
| Uniprot ID | |
| Function | Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrins alpha-M/beta-2 and alpha-X/beta-2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin alpha-X/beta-2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin alpha-M/beta-2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin alpha-M/beta-2 is also a receptor for factor X. Integrin alpha-D/beta-2 is a receptor for ICAM3 and VCAM1. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. |
| Molecular Weight | Theoretical: 82 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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