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Anti-NAV1.7 Polyclonal Antibody 2

Catalog No. TMAB-09255 Copy Product Info
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Anti-NAV1.7 Polyclonal Antibody 2 is a Rabbit antibody targeting NAV1.7. Anti-NAV1.7 Polyclonal Antibody 2 can be used in WB.

Anti-NAV1.7 Polyclonal Antibody 2

Copy Product Info
🥰Excellent
Catalog No. TMAB-09255

Anti-NAV1.7 Polyclonal Antibody 2 is a Rabbit antibody targeting NAV1.7. Anti-NAV1.7 Polyclonal Antibody 2 can be used in WB.

Anti-NAV1.7 Polyclonal Antibody 2
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-NAV1.7 Polyclonal Antibody 2 is a Rabbit antibody targeting NAV1.7. Anti-NAV1.7 Polyclonal Antibody 2 can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Dog,Cow,Rabbit)
Verified Activity
Sample: A549 Cell (Human) Lysate at 30 μg
Primary: Anti-NAV1.7 at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 219 kD
Observed band size: 219 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein. Note=In neurite terminals.
Tissue SpecificityExpressed strongly in dorsal root ganglion, with only minor levels elsewhere in the body, smooth muscle cells, MTC cell line and C-cell carcinoma. Isoform 1 is expressed preferentially in the central and peripheral nervous system. Isoform 2 is expressed preferentially in the dorsal root ganglion.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain disorder. [provided by RefSeq, Aug 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human SCN9A
Antigen Species
Human
Gene Name
SCN9A
Gene ID
Protein Name
Sodium channel protein type 9 subunit alpha
Uniprot ID
Function
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-sensitive Na(+) channel isoform. Plays a role in pain mechanisms, especially in the development of inflammatory pain.
Chemical Properties
Molecular WeightTheoretical: 219 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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