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Anti-GRM4 Polyclonal Antibody
Catalog No. TMAB-06793 Copy Product Info
🥰Excellent
Anti-GRM4 Polyclonal Antibody is a Rabbit antibody targeting GRM4. Anti-GRM4 Polyclonal Antibody can be used in WB.
Anti-GRM4 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-06793
Anti-GRM4 Polyclonal Antibody is a Rabbit antibody targeting GRM4. Anti-GRM4 Polyclonal Antibody can be used in WB.
Anti-GRM4 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-GRM4 Polyclonal Antibody is a Rabbit antibody targeting GRM4. Anti-GRM4 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Rabbit) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with GRM4 polyclonal antibody, unconjugated (TMAB-06793) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cell membrane. |
| Tissue Specificity | Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | L glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. |
| Immunogen | KLH conjugated synthetic peptide: human GRM4 |
| Antigen Species | Human |
| Gene Name | GRM4 |
| Gene ID | |
| Protein Name | Metabotropic glutamate receptor 4 |
| Uniprot ID | |
| Function | Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity. |
| Molecular Weight | Theoretical: 102 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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