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Anti-ILKAP Polyclonal Antibody
😃Good
Catalog No. TMAB-07684
Anti-ILKAP Polyclonal Antibody is a Rabbit antibody targeting ILKAP. Anti-ILKAP Polyclonal Antibody can be used in WB.
Anti-ILKAP Polyclonal Antibody
Anti-ILKAP Polyclonal Antibody
😃Good
Catalog No. TMAB-07684
Anti-ILKAP Polyclonal Antibody is a Rabbit antibody targeting ILKAP. Anti-ILKAP Polyclonal Antibody can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-ILKAP Polyclonal Antibody is a Rabbit antibody targeting ILKAP. Anti-ILKAP Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Cow) |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. |
| Tissue Specificity | Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3beta signaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2, which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome. |
| Immunogen | KLH conjugated synthetic peptide: human ILKAP |
| Antigen Species | Human |
| Gene Name | ILKAP |
| Gene ID | |
| Protein Name | Integrin-linked kinase-associated serine/threonine phosphatase 2C |
| Uniprot ID | |
| Function | Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation. |
| Molecular Weight | Theoretical: 43 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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