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Anti-SLC7A9 Polyclonal Antibody

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Catalog No. TMAB-12915

Anti-SLC7A9 Polyclonal Antibody is a Rabbit antibody targeting SLC7A9. Anti-SLC7A9 Polyclonal Antibody can be used in WB.

Anti-SLC7A9 Polyclonal Antibody

Anti-SLC7A9 Polyclonal Antibody

😃Good
Catalog No. TMAB-12915
Anti-SLC7A9 Polyclonal Antibody is a Rabbit antibody targeting SLC7A9. Anti-SLC7A9 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5277-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-SLC7A9 Polyclonal Antibody is a Rabbit antibody targeting SLC7A9. Anti-SLC7A9 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat)
Application
WB
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationMembrane; Multi-pass membrane protein.
Tissue SpecificityKidney, small intestine, liver and placenta.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundSLC7A9 belongs to the amino acid-polyamine-organocation (APC) superfamily. It is a disulfide linked heterodimer with the amino acid transport protein SLC3A1. SLC7A9 is involved in the high affinity, sodium independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high affinity reabsorption of cystine in the kidney tubule. Defects in SLC7A9 are a cause of non type I cystinuria (CSNU). CSNU arises from impaired transport of cystine and dibasic amino acids through the epithelial cells of the renal tubule and gastrointestinal tract. Three types of cystinuria have been described: type I (fully recessive or silent); type II (high excretor); type III (moderate excretor). Defects in SLC7A9 are associated with type II and type III cystinuria. They also might account for some non classic type I cystinuria cases.
Antigen Details
Immunogen
Recombinant Protein: human SLC7A9 protein
Antigen Species
Human
Gene Name
SLC7A9
Gene ID
11136
Protein Name
b(0,+)-type amino acid transporter 1
Uniprot ID
P82251
Function
Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system b(0,+)-like activity). Thought to be responsible for the high-affinity reabsorption of cystine in the kidney tubule.
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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