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Anti-Alpha-actinin-1 Polyclonal Antibody 2
Catalog No. TMAB-02486 Copy Product Info
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Anti-Alpha-actinin-1 Polyclonal Antibody 2 is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody 2 can be used in WB.
Anti-Alpha-actinin-1 Polyclonal Antibody 2
Copy Product Info🥰Excellent
Catalog No. TMAB-02486
Anti-Alpha-actinin-1 Polyclonal Antibody 2 is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody 2 can be used in WB.
Anti-Alpha-actinin-1 Polyclonal Antibody 2
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Alpha-actinin-1 Polyclonal Antibody 2 is a Rabbit antibody targeting Alpha-actinin-1. Anti-Alpha-actinin-1 Polyclonal Antibody 2 can be used in WB. |
| Reactivity | Mouse,Rat,Human |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with Alpha-actinin-1 polyclonal antibody, unconjugated (TMAB-02486) at 1:800 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm > cytoskeleton. Cytoplasm > myofibril > sarcomere > Z line. Cell membrane. Cell junction. Cell projection › ruffle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated Synthetic peptide: Human alpha Actinin 1/ACTN1 |
| Antigen Species | Human |
| Gene Name | ACTN1 |
| Gene ID | |
| Protein Name | alpha-actinin-1 |
| Uniprot ID | |
| Function | F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. |
| Molecular Weight | Theoretical: 103 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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