Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-11411

Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody is a Rabbit antibody targeting Phospho-VAV1 (Tyr174). Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody

Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody

Copy Product Info
😃Good
Catalog No. TMAB-11411
Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody is a Rabbit antibody targeting Phospho-VAV1 (Tyr174). Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2217-10 days7-10 days
100 μL$3717-10 days7-10 days
200 μL$5277-10 days7-10 days
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody is a Rabbit antibody targeting Phospho-VAV1 (Tyr174). Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Pig,Horse)
Verified Activity
Paraformaldehyde-fixed, paraffin embedded (rat spleen); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Incubation with (phospho-VAV1 (Tyr174)) Polyclonal Antibody, Unconjugated (TMAB-11411) at 1: 200 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining.
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Tissue SpecificityWidely expressed in hematopoietic cells but not in other cell types.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].
Antigen Details
Immunogen
KLH conjugated Synthesised phosphopeptide: human VAV1 around the phosphorylation site of Tyr174
Antigen Species
Human
Gene Name
VAV1
Gene ID
Protein Name
Proto-oncogene vav
Uniprot ID
Function
Couples tyrosine kinase signals with the activation of the Rho/Rac GTPases, thus leading to cell differentiation and/or proliferation.
Chemical Properties
Molecular WeightTheoretical: 98 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Dilution Calculator
  • Reconstitution Calculator
Related Tags: buy Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody | purchase Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody | Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody cost | order Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody | Anti-Phospho-VAV1 (Tyr174) Polyclonal Antibody molecular weight