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Anti-MC4R Polyclonal Antibody

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Catalog No. TMAB-08655

Anti-MC4R Polyclonal Antibody is a Rabbit antibody targeting MC4R. Anti-MC4R Polyclonal Antibody can be used in WB,ELISA.

Anti-MC4R Polyclonal Antibody

Anti-MC4R Polyclonal Antibody

😃Good
Catalog No. TMAB-08655
Anti-MC4R Polyclonal Antibody is a Rabbit antibody targeting MC4R. Anti-MC4R Polyclonal Antibody can be used in WB,ELISA.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2227-10 days7-10 days
100 μL$3747-10 days7-10 days
200 μL$5297-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-MC4R Polyclonal Antibody is a Rabbit antibody targeting MC4R. Anti-MC4R Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
Reactivity
Mouse,Rat (predicted:Human)
Application
Recommended Dose
WB: 1:500-2000; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane; Multi-pass membrane protein.
Tissue SpecificityBrain, placental, and gut tissues.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe melanocortin family comprises the Alpha-, Beta- and Gamma- melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human MC4 Receptor
Antigen Species
Human
Gene Name
MC4R
Gene ID
Protein Name
Melanocortin receptor 4
Uniprot ID
Function
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. This receptor is mediated by G proteins that stimulate adenylate cyclase.
Chemical Properties
Molecular WeightTheoretical: 37 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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