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Anti-SLC32A 1 Polyclonal Antibody
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Catalog No. TMAB-12888
Anti-SLC32A 1 Polyclonal Antibody is a Rabbit antibody targeting SLC32A 1. Anti-SLC32A 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
Anti-SLC32A 1 Polyclonal Antibody
Anti-SLC32A 1 Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-12888
Anti-SLC32A 1 Polyclonal Antibody is a Rabbit antibody targeting SLC32A 1. Anti-SLC32A 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | Anti-SLC32A 1 Polyclonal Antibody is a Rabbit antibody targeting SLC32A 1. Anti-SLC32A 1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,ICC/IF,IF,WB. |
| Ig Type | IgG |
| Reactivity | Mouse,Rat (predicted:Human,Pig,Cow,Rabbit,Sheep) |
| Verified Activity | 25 μg total protein per lane of various lysates (see on figure) probed with SLC32A 1 polyclonal antibody, unconjugated (TMAB-12888) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r. T. for 60 min. |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasmic vesicle membrane; Multi-pass membrane protein |
| Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Synaptic transmission involves the controlled exocytosis of vesicles containing specific neurotransmitters. Usually, neurotransmitters are synthesized in the cytoplasm of the cell and must be transported into synaptic vesicles for release. The vesicular GABA transporter (VGAT) is responsible for loading γ-aminobutyric acid (GABA), an inhibitory neurotransmitter, from neuronal cytoplasm into synaptic vesicles and is expressed only in the nerve endings of inhibitory neurons that contain GABA and/or glycine. During neocortical development, VGAT expression barely precedes the maturation of inhibitory synaptogenesis, suggesting that it may contribute to the development of neocortical GABAergic circuitry. VGAT may also play a role in epileptogenesis and the recovery mechanisms that occur after a spontaneous seizure. |
| Immunogen | KLH conjugated synthetic peptide: human SLC32A1 |
| Antigen Species | Human |
| Gene Name | SLC32A1 |
| Gene ID | |
| Protein Name | Vesicular inhibitory amino acid transporter |
| Uniprot ID | |
| Function | Involved in the uptake of GABA and glycine into the synaptic vesicles. |
| Molecular Weight | Theoretical: 57 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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