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Anti-L2HGDH Polyclonal Antibody
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Catalog No. TMAB-08179
Anti-L2HGDH Polyclonal Antibody is a Rabbit antibody targeting L2HGDH. Anti-L2HGDH Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Anti-L2HGDH Polyclonal Antibody
Anti-L2HGDH Polyclonal Antibody
Copy Product Info😃Good
Catalog No. TMAB-08179
Anti-L2HGDH Polyclonal Antibody is a Rabbit antibody targeting L2HGDH. Anti-L2HGDH Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-L2HGDH Polyclonal Antibody is a Rabbit antibody targeting L2HGDH. Anti-L2HGDH Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Pig,Cow,Horse,Rabbit,Sheep, Orangutan) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (L2 hGDH) Polyclonal Antibody, Unconjugated (TMAB-08179) at 1:400 overnight at 4°C, followed by operating according to SP Kit (Rabbit) instructions and DAB staining. 2. Sample: Pancreas (Mouse) Lysate at 40 μg Primary: Anti-L2 hGDH (TMAB-08179) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 45 kD Observed band size: 48 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Mitochondrion. |
| Tissue Specificity | Widely expressed. Highly expressed in brain, testis and muscle. Expressed to a lower extent in lymphocytes, fibroblasts, keratinocytes, placenta, bladder, small intestine, liver and bone marrow. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes L-2-hydroxyglutarate dehydrogenase, a FAD-dependent enzyme that oxidizes L-2-hydroxyglutarate to alpha-ketoglutarate in a variety of mammalian tissues. Mutations in this gene cause L-2-hydroxyglutaric aciduria, a rare autosomal recessive neurometabolic disorder resulting in moderate to severe mental retardation. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human L2HGDH |
| Antigen Species | Human |
| Gene Name | L2HGDH |
| Gene ID | |
| Protein Name | L-2-hydroxyglutarate dehydrogenase, mitochondrial |
| Uniprot ID |
| Molecular Weight | Theoretical: 45 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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