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Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2
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Catalog No. TMAB-10927
Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MAP2 (Ser136). Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2
Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2
😃Good
Catalog No. TMAB-10927
Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MAP2 (Ser136). Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MAP2 (Ser136). Anti-Phospho-MAP2 (Ser136) Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM. |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 0.2μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm, cytoskeleton (Probable). |
| Construction | Hybridoma Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton. |
| Immunogen | KLH conjugated synthesised phosphopeptide: human MAP2 around the phosphorylation site of Ser136 |
| Antigen Species | Human |
| Gene Name | MAP2 |
| Gene ID | |
| Protein Name | Microtubule-associated protein 2 |
| Uniprot ID | |
| Function | The exact function of MAP2 is unknown but MAPs may stabilize the microtubules against depolymerization. They also seem to have a stiffening effect on microtubules. |
| Molecular Weight | Theoretical: 70/201 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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