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Anti-HAP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-06883
Anti-HAP1 Polyclonal Antibody is a Rabbit antibody targeting HAP1. Anti-HAP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Anti-HAP1 Polyclonal Antibody
Anti-HAP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-06883
Anti-HAP1 Polyclonal Antibody is a Rabbit antibody targeting HAP1. Anti-HAP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $371 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-HAP1 Polyclonal Antibody is a Rabbit antibody targeting HAP1. Anti-HAP1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Rat (predicted:Human,Mouse,Rabbit) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Tissue Specificity | Predominantly expressed in brain. Selectively expressed in neurons. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | Preservative: 0.02% Proclin300, Constituents: 1% BSA, 0.01M PBS, pH7.4. |
| Concentration | 1mg/ml |
| Research Background | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human HAP1 |
| Antigen Species | Human |
| Gene Name | HAP1 |
| Gene ID | |
| Protein Name | Huntingtin-associated protein 1 |
| Uniprot ID | |
| Function | Associates specifically with huntingtin. This binding is enhanced by an expanded polyglutamine repeat. |
| Molecular Weight | Theoretical: 75 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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