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Anti-CITED1 Polyclonal Antibody
Catalog No. TMAB-04365 Copy Product Info
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Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB.
Anti-CITED1 Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-04365
Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB.
Anti-CITED1 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $374 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | Sample: Lane 1: Mouse Testis tissue lysates Lane 2: Mouse B16 cell lysates Lane 3: Human SH-SY5Y cell lysates Lane 4: Human 293T cell lysates Primary: Anti-CITED1 (TMAB-04365) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 20 kDa Observed band size: 20 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner. |
| Tissue Specificity | Expressed only in melanocytes and testis. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | This gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009] |
| Immunogen | KLH conjugated synthetic peptide: human CITED1/ABCC1 |
| Antigen Species | Human |
| Gene Name | CITED1 |
| Gene ID | |
| Protein Name | Cbp/p300-interacting transactivator 1 |
| Uniprot ID | |
| Function | Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner. |
| Molecular Weight | Theoretical: 20 kDa. Actual: 20 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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