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Anti-CITED1 Polyclonal Antibody

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Catalog No. TMAB-04365

Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB.

Anti-CITED1 Polyclonal Antibody

Anti-CITED1 Polyclonal Antibody

Copy Product Info
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Catalog No. TMAB-04365
Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 μL$2207-10 days7-10 days
100 μL$3747-10 days7-10 days
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Anti-CITED1 Polyclonal Antibody is a Rabbit antibody targeting CITED1. Anti-CITED1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human,Mouse
Verified Activity
Sample:
Lane 1: Mouse Testis tissue lysates
Lane 2: Mouse B16 cell lysates
Lane 3: Human SH-SY5Y cell lysates
Lane 4: Human 293T cell lysates
Primary: Anti-CITED1 (TMAB-04365) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 20 kDa
Observed band size: 20 kDa
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm by a nuclear export signal and (NES) in a CRM1-dependent manner.
Tissue SpecificityExpressed only in melanocytes and testis.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes a member of the CREB-binding protein/p300-interacting transactivator with Asp/Glu-rich C-terminal domain (CITED) family of proteins. The encoded protein, also known as melanocyte-specific gene 1, may function as a transcriptional coactivator and may play a role in pigmentation of melanocytes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2009]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human CITED1/ABCC1
Antigen Species
Human
Gene Name
CITED1
Gene ID
Protein Name
Cbp/p300-interacting transactivator 1
Uniprot ID
Function
Transcriptional coactivator of the p300/CBP-mediated trancription complex. Enhances SMAD-mediated transcription by strengthening the functional link between the DNA-binding SMAD transcription factors and the p300/CBP transcription coactivator complex. Stimulates estrogen-dependent transactivation activity mediated by estrogen receptors signaling; stabilizes the interaction of estrogen receptor ESR1 and histone acetyltransferase EP300. Positively regulates TGF-beta signaling through its association with the SMAD/p300/CBP-mediated transcriptional coactivator complex. Induces transcription from estrogen-responsive promoters and protection against cell death. Potentiates EGR2-mediated transcriptional activation activity from the ERBB2 promoter. Acts as an inhibitor of osteoblastic mineralization through a cAMP-dependent parathyroid hormone receptor signaling. May play a role in pigmentation of melanocytes. Associates with chromatin to the estrogen-responsive TGF-alpha promoter region in a estrogen-dependent manner.
Chemical Properties
Molecular WeightTheoretical: 20 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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