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Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody
Catalog No. TMAB-11169 Copy Product Info
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Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG 2 (Tyr1217). Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody can be used in FCM,ELISA.
Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-11169
Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG 2 (Tyr1217). Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody can be used in FCM,ELISA.
Anti-Phospho-PLCG 2
(Tyr1217) Polyclonal Antibody
(Tyr1217) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
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| Description | Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody is a Rabbit antibody targeting Phospho-PLCG 2 (Tyr1217). Anti-Phospho-PLCG 2 (Tyr1217) Polyclonal Antibody can be used in FCM,ELISA. |
| Ig Type | IgG |
| Reactivity | Human,Rabbit (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow,Horse,GuineaPig) |
| Verified Activity | 1. phosphopeptide non phosphopeptide 2. Blank control (blue): Hep G2 Cells (fixed with 2% paraformaldehyde (10 min) and then permeabilized with ice-cold 90% methanol for 30 min on ice). Primary Antibody: Rabbit Anti-Phospho-PLCG 2 (Tyr1217)/AF647 Conjugated antibody (TMAB-11169/AF647), Dilution: 1 μg in 100 μL 1X PBS containing 0.5% BSA; Isotype Control Antibody: Rabbit IgG/AF647 (orange), used under the same conditions. |
| Application | |
| Recommended Dose | FCM: 1μg/Test; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | Enzymes of the phospholipase C family catalyze the hydrolysis of phospholipids to yield diacylglycerols and water soluble phosphorylated derivatives of the lipid head groups. A number of these enzymes have specificity for phosphoinositides. Of the phosphoinositide specific phospholipase C enzymes, C beta is regulated by heterotrimeric G protein coupled receptors, while the closely related C gamma 1 and C gamma 2 enzymes are controlled by receptor tyrosine kinases. The C gamma 1 and C gamma 2 enzymes are composed of phospholipase domains that flank regions of homology to noncatalytic domains of the SRC oncogene product, SH2 and SH3. |
| Immunogen | KLH conjugated Synthesised phosphopeptide: human PLC gamma 2 around the phosphorylation site of Tyr1217 |
| Antigen Species | Human |
| Gene Name | PLCG2 |
| Gene ID | |
| Protein Name | 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase gamma-2 |
| Uniprot ID | |
| Function | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling. |
| Molecular Weight | Theoretical: 147 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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