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Anti-FBH1 Polyclonal Antibody

Catalog No. TMAB-05910 Copy Product Info
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Anti-FBH1 Polyclonal Antibody is a Rabbit antibody targeting FBH1. Anti-FBH1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FBH1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05910

Anti-FBH1 Polyclonal Antibody is a Rabbit antibody targeting FBH1. Anti-FBH1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.

Anti-FBH1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3727-10 days7-10 days
200 μL$5277-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FBH1 Polyclonal Antibody is a Rabbit antibody targeting FBH1. Anti-FBH1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
Reactivity
Rat (predicted:Human,Mouse,Dog,Horse)
Verified Activity
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer (0.01 M, pH 6.0), Boiling bathing for 15 min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30 min; Blocking buffer (normal goat serum) at 37℃ for 20 min;
Incubation: Anti-FBXO18 Polyclonal Antibody, Unconjugated (TMAB-05910) 1: 200, overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining
Application
Recommended Dose
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNuclear
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundFBXO18 belongs to the F-box protein family, whose members share the F-box, an approximately 40 amino acid motif. It has both DNA-dependent ATPase and DNA unwinding activities. FBXO18 is a 1,043 amino acid protein encoded by the human gene FBXO18. FBXO18 belongs to the helicase family (UvrD subfamily) and contains one F-box domain. This nuclear protein is a DNA-dependent ATPase that unwinds double-stranded DNA in a 3' to 5' direction. FBXO18 also recognizes and binds to a variety of phosphorylated proteins and promotes their ubiquitination and degradation. It also interacts with Skp1 in the SCF E3 ubiquitin ligase complex consisting of Skp1, CUL-1, Rbx1 and FBXO18.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FBXO18
Antigen Species
Human
Gene Name
FBH1
Gene ID
Protein Name
F-box DNA helicase 1
Uniprot ID
Function
DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.
Chemical Properties
Molecular WeightTheoretical: 118 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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