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Anti-Contactin 1 Polyclonal Antibody
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Catalog No. TMAB-04565
Anti-Contactin 1 Polyclonal Antibody is a Rabbit antibody targeting Contactin 1. Anti-Contactin 1 Polyclonal Antibody can be used in FCM.
Anti-Contactin 1 Polyclonal Antibody
Anti-Contactin 1 Polyclonal Antibody
😃Good
Catalog No. TMAB-04565
Anti-Contactin 1 Polyclonal Antibody is a Rabbit antibody targeting Contactin 1. Anti-Contactin 1 Polyclonal Antibody can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Contactin 1 Polyclonal Antibody is a Rabbit antibody targeting Contactin 1. Anti-Contactin 1 Polyclonal Antibody can be used in FCM. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | FCM: 3μg/Test |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Isoform 1: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side.Isoform 2: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. |
| Tissue Specificity | Strongly expressed in brain and in neuroblastoma and retinoblastoma cell lines. Lower levels of expression in lung, pancreas, kidney and skeletal muscle. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Immunogen | KLH conjugated synthetic peptide: human Contactin 1 |
| Antigen Species | Human |
| Gene Name | CNTN1 |
| Gene ID | |
| Protein Name | Contactin-1 |
| Uniprot ID | |
| Function | Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth (By similarity). |
| Molecular Weight | Theoretical: 111 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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