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Anti-LXR beta Polyclonal Antibody
Catalog No. TMAB-08460 Copy Product Info
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Anti-LXR beta Polyclonal Antibody is a Rabbit antibody targeting LXR beta. Anti-LXR beta Polyclonal Antibody can be used in WB.
Anti-LXR beta Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAB-08460
Anti-LXR beta Polyclonal Antibody is a Rabbit antibody targeting LXR beta. Anti-LXR beta Polyclonal Antibody can be used in WB.
Anti-LXR beta Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-LXR beta Polyclonal Antibody is a Rabbit antibody targeting LXR beta. Anti-LXR beta Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Mouse (predicted:Human,Rat,Dog,Pig,Cow,Sheep) |
| Verified Activity | Sample: small intestine (Mouse) Lysate at 40 μg Primary: Anti-LXR betA (TMAB-08460) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 51 kD Observed band size: 51 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Nucleus. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010] |
| Immunogen | KLH conjugated synthetic peptide: human LXR beta |
| Antigen Species | Human |
| Gene Name | NR1H2 |
| Gene ID | |
| Protein Name | Oxysterols receptor LXR-beta |
| Uniprot ID | |
| Function | Orphan receptor. Binds preferentially to double-stranded oligonucleotide direct repeats having the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). Regulates cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. |
| Molecular Weight | Theoretical: 51 kDa. Actual: 51 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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