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Anti-SCNN1B Polyclonal Antibody
😃Good
Catalog No. TMAB-12589
Anti-SCNN1B Polyclonal Antibody is a Rabbit antibody targeting SCNN1B. Anti-SCNN1B Polyclonal Antibody can be used in WB,ICC/IF.
Anti-SCNN1B Polyclonal Antibody
Anti-SCNN1B Polyclonal Antibody
😃Good
Catalog No. TMAB-12589
Anti-SCNN1B Polyclonal Antibody is a Rabbit antibody targeting SCNN1B. Anti-SCNN1B Polyclonal Antibody can be used in WB,ICC/IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $220 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-SCNN1B Polyclonal Antibody is a Rabbit antibody targeting SCNN1B. Anti-SCNN1B Polyclonal Antibody can be used in WB,ICC/IF. |
| Ig Type | IgG |
| Reactivity | Human (predicted:Mouse,Rat,Pig,Horse,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; ICC/IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Apical cell membrane; Multi-pass membrane protein. Note=Apical membrane of epithelial cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | SCNN1B is a subunit of the epithelial sodium channel, ENaC. ENac has high sodium selectivity, low conductance, and amiloride sensitivity. The functional channel of ENaC is composed of at least 3 subunits, alpha (SCNN1A), beta (SCNN1B), and gamma (SCNN1G). The 3 subunits show sequence similarities to one another, indicating descent from a common ancestral gene. Each encodes a protein containing 2 transmembrane domains, with intracellular amino and carboxyl termini. |
| Immunogen | KLH conjugated synthetic peptide: human SCNN1B |
| Antigen Species | Human |
| Gene Name | SCNN1B |
| Gene ID | |
| Protein Name | Epithelial sodium channel subunit beta |
| Uniprot ID | |
| Function | Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception. |
| Molecular Weight | Theoretical: 73 kDa. Actual: 95-100/65-75 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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