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Anti-GOLPH3 Polyclonal Antibody

Catalog No. TMAB-06637 Copy Product Info
🥰Excellent
Anti-GOLPH3 Polyclonal Antibody is a Rabbit antibody targeting GOLPH3. Anti-GOLPH3 Polyclonal Antibody can be used in WB.

Anti-GOLPH3 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-06637

Anti-GOLPH3 Polyclonal Antibody is a Rabbit antibody targeting GOLPH3. Anti-GOLPH3 Polyclonal Antibody can be used in WB.

Anti-GOLPH3 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2227-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-GOLPH3 Polyclonal Antibody is a Rabbit antibody targeting GOLPH3. Anti-GOLPH3 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human (predicted:Mouse,Rat,Chicken,Dog,Cow,Horse)
Verified Activity
Sample: Hela (Human) Cell Lysate at 30 μg
Primary: Anti-GOLPH3 (TMAB-06637) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 34 kD
Observed band size: 33 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationCell membrane. Endosome. Cytoplasm. Golgi apparatus > Golgi stack membrane. Mitochondrion intermembrane space.
Tissue SpecificityDetected in muscle fibers of patients with mitochondrial diseases; not detected in normal muscle fibers.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThe Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. GOLPH3L (golgi phosphoprotein 3-like), also known as GPP34R, is a 285 amino acid cytoplasmic protein that localizes to the Golgi apparatus. Belonging to the GOLPH3/VPS74 family, GOLPH3L may have a regulatory role in Golgi trafficking. GOLPH3L is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human GOLPH3
Antigen Species
Human
Gene Name
GOLPH3
Gene ID
Protein Name
Golgi phosphoprotein 3
Uniprot ID
Function
Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene.
Chemical Properties
Molecular WeightTheoretical: 34 kDa. Actual: 33 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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