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Anti-FEN1 Polyclonal Antibody

Catalog No. TMAB-05961 Copy Product Info
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Anti-FEN1 Polyclonal Antibody is a Rabbit antibody targeting FEN1. Anti-FEN1 Polyclonal Antibody can be used in WB.

Anti-FEN1 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-05961

Anti-FEN1 Polyclonal Antibody is a Rabbit antibody targeting FEN1. Anti-FEN1 Polyclonal Antibody can be used in WB.

Anti-FEN1 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2207-10 days7-10 days
100 μL$3737-10 days7-10 days
200 μL$5287-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FEN1 Polyclonal Antibody is a Rabbit antibody targeting FEN1. Anti-FEN1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample: Bone (Mouse) Lysate at 40 μg
Primary: Anti-FEN1 (TMAB-05961) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 42 kD
Observed band size: 40 kD
Application
Recommended Dose
WB: 1:500-2000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationNucleus, nucleolus. Nucleus, nucleoplasm. Mitochondrion. Note=Resides mostly in the nucleoli and relocalizes to the nucleoplasm upon DNA damage.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundStructure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human FEN1
Antigen Species
Human
Gene Name
FEN1
Gene ID
Protein Name
Flap endonuclease 1
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 42 kDa. Actual: 40 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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