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Anti-HSD3B7 Polyclonal Antibody

Catalog No. TMAB-07325 Copy Product Info
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Anti-HSD3B7 Polyclonal Antibody is a Rabbit antibody targeting HSD3B7. Anti-HSD3B7 Polyclonal Antibody can be used in WB,ELISA.

Anti-HSD3B7 Polyclonal Antibody

Copy Product Info
🥰Excellent
Catalog No. TMAB-07325

Anti-HSD3B7 Polyclonal Antibody is a Rabbit antibody targeting HSD3B7. Anti-HSD3B7 Polyclonal Antibody can be used in WB,ELISA.

Anti-HSD3B7 Polyclonal Antibody
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2217-10 days7-10 days
100 μL$3727-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-HSD3B7 Polyclonal Antibody is a Rabbit antibody targeting HSD3B7. Anti-HSD3B7 Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse)
Verified Activity
Sample:
Lane 1: Human HeLa cell lysates
Lane 2: Human HepG2 cell lysates
Lane 3: Human MCF-7 cell lysates
Lane 4: Human A549 cell lysates
Primary: Anti-HSD3B7 (TMAB-07325) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 41 kDa
Observed band size: 45 kDa
Application
Recommended Dose
WB: 1:500-2000; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue SpecificityHigh levels in liver and lung, moderate levels in spleen, brain, heart, kidney, jejunum and testis. Up-regulated in 3Y1 cells upon growth arrest.
ConstructionPolyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration1mg/ml
Research BackgroundThis gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008].
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human HSD3B7
Antigen Species
Human
Gene Name
HSD3B7
Gene ID
Protein Name
3 beta-hydroxysteroid dehydrogenase type 7
Uniprot ID
Function
The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. HSD VII is active against four 7-alpha-hydroxylated sterols. Does not metabolize several different C(19/21) steroids as substrates. Involved in bile acid synthesis.
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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