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Anti-GCC1 Polyclonal Antibody is a Rabbit antibody targeting GCC1. Anti-GCC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-GCC1 Polyclonal Antibody is a Rabbit antibody targeting GCC1. Anti-GCC1 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Horse,Sheep) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | GCC1 is a 775 amino acid cytoplasmic and peripheral membrane protein of the Golgi apparatus. Involved in maintenance of Golgi structure, GCC1 is essential for retrograde transport of cargo from the early endosomes to the trans-Golgi network. GCC1 contains one GRIP domain and is encoded by a gene that maps to human chromosome 7q32.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. |
| Immunogen | KLH conjugated synthetic peptide: human GCC1 |
| Antigen Species | Human |
| Gene Name | GCC1 |
| Gene ID | |
| Protein Name | GRIP and coiled-coil domain-containing protein 1 |
| Uniprot ID | |
| Function | GCC1 is a peripheral membrane protein and is sensitive to brefeldin A. GCC1 contains a GRIP domain which is thought to be used in targeting. It may play a role in the organization of trans-Golgi network subcompartment involved with membrane transport. |
| Molecular Weight | Theoretical: 88 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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